[3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester
[3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester
CAS: 1073353-90-8
Molecular Formula: C19H24BNO2
[3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester - Names and Identifiers
[3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester - Physico-chemical Properties
| Molecular Formula | C19H24BNO2 |
| Molar Mass | 309.21 |
| Melting Point | 112-115°C |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD09266198 |
[3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester - Introduction
[3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester is an organic compound, also known as [3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless or light yellow solid
-Molecular formula: C24H31BN2O2
-Molecular weight: 388.33g/mol
-Melting point: about 80-85 degrees Celsius
-Soluble: Soluble in common organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane
Use:
[3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester is commonly used as a coupling reagent for aromatic amines and boronic acid groups in organic synthesis. It can react with an active hydrogen atom-containing moiety of an organic compound to form a coupled product. Such compounds can be used in the construction of heterocycles, drug synthesis and other applications in organic synthesis.
Preparation Method:
The method of preparing [3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester usually includes the following steps:
1.2-phenylboronic acid reacts with the corresponding nucleophile to generate boronic ester.
2. reacting boronic ester with appropriate amine to form [3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester.
Safety Information:
[3-(Phenylaminomethyl)phenyl]-boronic specific safety information for the acid pinacol ester varies from vendor to vendor, please refer to the relevant safety data sheet. Appropriate personal protective equipment, such as chemical protective gloves and eye protection, must be worn during use. In addition, the laboratory's safe practices and waste disposal guidelines should be followed to ensure safety.
Nature:
-Appearance: Colorless or light yellow solid
-Molecular formula: C24H31BN2O2
-Molecular weight: 388.33g/mol
-Melting point: about 80-85 degrees Celsius
-Soluble: Soluble in common organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane
Use:
[3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester is commonly used as a coupling reagent for aromatic amines and boronic acid groups in organic synthesis. It can react with an active hydrogen atom-containing moiety of an organic compound to form a coupled product. Such compounds can be used in the construction of heterocycles, drug synthesis and other applications in organic synthesis.
Preparation Method:
The method of preparing [3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester usually includes the following steps:
1.2-phenylboronic acid reacts with the corresponding nucleophile to generate boronic ester.
2. reacting boronic ester with appropriate amine to form [3-(Phenylaminomethyl)phenyl]-boronic acid pinacol ester.
Safety Information:
[3-(Phenylaminomethyl)phenyl]-boronic specific safety information for the acid pinacol ester varies from vendor to vendor, please refer to the relevant safety data sheet. Appropriate personal protective equipment, such as chemical protective gloves and eye protection, must be worn during use. In addition, the laboratory's safe practices and waste disposal guidelines should be followed to ensure safety.
Last Update：2024-04-09 20:52:54
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